By Sarah P. O’BrienAUSTRALIA NEWS ServiceIn a series of papers published in the British Journal of Pharmacology (BJPs) this month, scientists at Imperial College London have reported a novel way to identify the best nicotine salt for different types of nicotine users.
Researchers from Imperial College said the new method could reduce the amount of nicotine in the solution of the tobacco and sugar-based products.
The scientists said they developed a technique called ion chromatography-mass spectrometry (ICS-MS) that uses atomic force microscopy to identify specific molecules in liquids.
The technique could help users find the most effective nicotine salt in liquid nicotine products.
ICS-M Schematic, a new ion chromatographic technique developed by Imperial College researchers.
The method has been widely used for other pharmaceuticals, such as cough and cold medicines, and has been used to identify new drugs that can be used to treat certain conditions.
ICS-M has been described as the “first in-vivo method to determine the composition of liquid nicotine salts”.
The research was led by Professor David O’Neill, the Institute of Chemical Biology and Chemistry, Imperial College and the School of Chemistry.
“Ionic chromatography can be applied to a variety of liquids and can help identify compounds in liquids that are likely to contain a specific molecular structure or activity, or are likely likely to have some property that might benefit in terms of drug efficacy,” Dr O’Neil said.
Professor O’Connor said ion chromography could be used in other applications.
“The key to this technique is the ability to identify individual ions, the smallest units of a molecule, so that you can then analyse these ions and determine the exact structure of the molecule,” he said.
“This method can also be used for the analysis of other substances, for example, for the synthesis of polysaccharides or proteins, which could be very important in drug development and manufacturing.”ICS has also been used for testing new drugs, such for the development of vaccines, in animal studies.
Nicotine salt and the future of smokingNicotine is the main ingredient in tobacco and other products.
It has a range of other effects on the body including anxiety, addiction and obesity.
But while nicotine is known to have a number of addictive properties, it is also a known stimulant and is not addictive.
In addition, the vast majority of people do not smoke.
The average adult cigarette smoker is expected to quit in his or her 20s, according to the World Health Organization (WHO).
Nicotine salts are usually used in liquid form, but they are also often used in a mixture in which a small amount of other ingredients is added.
Scientists have used the method to identify which nicotine salt was the most potent nicotine, and found the best-tasting liquid was the nicotine salt juuju.
However, the new technique may not be useful in the long term for nicotine, because nicotine salts can be extracted from sugar, sugar-like carbohydrates and starch and used in products such as chewing gum, candies and cigarettes.
“Although ion chromochemical methods can be useful for identifying nicotine salts, they can be a poor indicator of the composition and activity of liquids in which nicotine salts are present,” Dr Sallam said.
“We have shown that ion chroma-mass-spectrometry can be more effective than other approaches for identifying specific nicotine salts in liquids.”